Fertility conservation: Understand your choices before cancer treatment

Cancer treatment can have a significant influence on fertility. Get the truths about fertility conservation choices and understand how to pick what’s right for you.

By Mayo Clinic Staff

If you’re being dealt with for cancer, you may have concerns about fertility conservation. Learn how cancer treatment can impact your capability to have a kid, along with what fertility conservation actions you can take before you start cancer treatment.

How does cancer treatment impact fertility?

Particular cancer treatments can hurt your fertility. The impacts may be momentary or irreversible. The probability that cancer treatment will hurt your fertility depends upon the type and phase of cancer, the kind of cancer treatment, and your age at the time of treatment. Cancer treatments and their results may consist of:

  • Surgical treatment. Fertility can be hurt by the surgical elimination of the testicles, uterus or ovaries.
  • Chemotherapy. The results depend upon the drug and the dosage. The most damage is triggered by drugs called alkylating representatives and the drug cisplatin. More youthful ladies who get chemotherapy are less most likely to end up being sterile than are older females.
  • Radiation. Radiation can be more destructive to fertility than chemotherapy, depending upon the area and size of the radiation field and the dosage offered. High dosages of radiation can ruin some or all of the eggs in the ovaries.
  • Other cancer medications. Hormonal agent treatments utilized to deal with specific cancers, consisting of breast cancer in females, can impact fertility. The results are frequently reversible. As soon as treatment stops, fertility may be brought back.

When should I speak to my medical professional about fertility conservation?

If you are preparing cancer treatment and wish to maintain your fertility, talk with your physician and a fertility expert as quickly as possible. A fertility professional can assist you comprehend your choices, response concerns and function as your fertility supporter throughout your treatment.

Your fertility can be harmed by a single cancer treatment session, and for ladies, some approaches of fertility conservation are generally done throughout particular stages of the menstruation. Ask if you will require to postpone cancer treatment to take fertility conservation actions and, if so, how this may impact your cancer.

How can females protect fertility before cancer treatment?

Females who will go through cancer treatment have different alternatives when it pertains to fertility conservation. :

  • Embryo cryopreservation. This treatment includes gathering eggs, fertilizing them and freezing them so they can be implanted at a later date. Research study reveals that embryos can endure the freezing and thawing procedure approximately 90% of the time.
  • Egg freezing (oocyte cryopreservation). In this treatment, you’ll have your unfertilized eggs gathered and frozen. Human eggs do not make it through freezing along with human embryos.
  • Radiation protecting. In this treatment, little lead guards are positioned over the ovaries to lower the quantity of radiation direct exposure they get.
  • Ovarian transposition (oophoropexy). Throughout this treatment, the ovaries are surgically rearranged in the hips so they’re out of the radiation field when radiation is provided to the pelvic location. Due to the fact that of scatter radiation, ovaries aren’t constantly safeguarded. After treatment, you may require to have your ovaries rearranged once again to develop.
  • Surgical elimination of the cervix. To deal with early-stage cervical cancer, a big cone-shaped area of the cervix, consisting of the malignant location, is gotten rid of (cervical conization). The rest of the cervix and the uterus are protected. A cosmetic surgeon can partly or totally get rid of the cervix and the connective tissues next to the uterus and cervix (extreme trachelectomy).

What can guys do to maintain fertility before cancer treatment?

Male likewise can take actions to maintain their fertility before going through cancer treatment. :

  • Sperm cryopreservation. This treatment includes freezing and saving sperm at a fertility center or sperm bank for usage at a later date. Samples are frozen and can be kept for several years.
  • Radiation protecting. In this treatment, little lead guards are put over the testicles to lower the quantity of radiation direct exposure they get.

What can moms and dads do to maintain the fertility of a kid who has cancer?

Fertility must be gone over with kids dealt with for cancer as quickly as they are old adequate to comprehend. Your permission and your kid’s may be needed before a treatment can be done.

If your kid has actually started the age of puberty, alternatives may consist of oocyte or sperm cryopreservation.

Women who have cancer treatment before adolescence can select ovarian tissue cryopreservation. Throughout this treatment, ovarian tissue is surgically gotten rid of, frozen and later on defrosted and reimplanted.

One approach being looked into to protect fertility in kids who have cancer treatment before the age of puberty is a treatment in which testicular tissue is surgically gotten rid of and frozen.

Can fertility conservation disrupt effective cancer treatment or increase the threat of repeating cancer?

There’s no proof that present fertility conservation techniques can straight jeopardize the success of cancer treatments. You might jeopardize the success of your treatment if you postpone surgical treatment or chemotherapy to pursue fertility conservation.

There seems no increased danger of cancer reoccurrence related to a lot of fertility conservation techniques. There is an issue that reimplanting frozen tissue might reestablish cancer cells– depending on the type and phase of cancer.

Can cancer treatment increase the danger of health issue in kids developed later?

As long as you do not expose your child to cancer treatments in utero, cancer treatments do not appear to increase the danger of hereditary conditions or other health issue for future kids.

If you get a cancer treatment that impacts the performance of your heart or lungs or if you get radiation in your pelvic location, talk to a professional before ending up being pregnant to prepare for possible pregnancy issues.

How do I figure out the very best fertility conservation alternative for me?

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Your medical group will think about the kind of cancer you have, your treatment strategy and the quantity of time you have before treatment starts to assist figure out the very best technique for you.

The medical diagnosis of cancer and the treatment procedure can be frustrating. If you’re worried about how cancer treatment may impact your fertility, you have alternatives. Do not wait. Getting info about fertility conservation techniques before you start cancer treatment can assist you make an educated option.

March 07, 2024

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  6. The Ethics Committee of the American Society for Reproductive Medicine. Fertility conservation and recreation in clients dealing with gonadotoxic treatments: A principles committee viewpoint. Fertility and Sterility. 2018; doi: 10.1016/ j.fertnstert.
  7. How cancer treatments can impact fertility in ladies. American Cancer Society. https://www.cancer.org/treatment/treatments-and-side-effects/physical-side-effects/fertility-and-sexual-side-effects/fertility-and-women-with-cancer/how-cancer-treatments-affect-fertility.html. Accessed July 2, 2019.
  8. Long CJ, et al. Fertility conservation in kids and teenagers with cancer. Urology. 2016; 91:190.

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